Via Interstate 44 East, you have access to the following interstates:
Highway 40 / Interstate 64 is still undergoing construction. Currently it begins in O'Fallon, crosses I-270, continues through Downtown St. Louis, and continues to the east coast. Interstate 55 continues out of St. Louis to Chicago, Illinois.
Interstate 70 offers access to Lambert-St. Louis International Airport.
Interstate 170 connects I-64 to I-270.
Interstate 270 circles around the St. Louis Metropolitan Area, connecting with I-70, I-64, I-55, and I-44.
Interstate 44 West
Interstate 44 West continues through Rolla, Springfield, Joplin, and leaves Missouri.